Contrast‐enhanced wide‐angle high‐speed polarization modulator for active‐retarder 3‐D displays

Abstract— A contrast‐enhanced wide‐angle high‐speed polarization modulator for active‐retarder 3‐D displays is proposed. By using a double liquid‐crystal‐cell structure together with a dedicated driving scheme and an external quarter‐wave retarder, a high‐performance modulator can be realized, resulting in minimized brightness loss and low cross‐talk levels in fast‐refresh time‐multiplexed 3‐D displays.     

A novel quarter‐wave retardation film for improving viewing angle properties in time‐sequential stereoscopic 3D‐LCDs

We have successfully developed a quarter‐wave retardation film (QWF) for wide viewing angle 3D liquid crystal displays (3D‐LCDs) that provides high luminance, low crosstalk, low color change, and low head‐tilt‐angle dependency. It was found that the out‐of‐plane retardation (Rth) of the QWF in the LCD needs to be close to 0 nm in order to improve the 3D display properties at an off‐axis position and that the in‐plane retardation (Re) needs to be adjusted from 120 to 130 nm to achieve low color change with head tilting. We adopted a coating process for making our QWF because of its potential for retardation control. 3D‐LCDs with this QWF whose Rth was nearly zero had high performance and allowed off‐axis other than on‐axis.     

Design of a two‐level controller for an active suspension system

The paper focuses on a control design for a vehicle suspension system in which a balance between different performance demands is achieved. The starting point of the control design is a full–car model which contains nonlinear components, i.e. the dynamics of the dampers and springs and nonlinear actuator dynamics. In order to handle the high complexity of the problem this paper proposes the design of a two‐level controller of an active suspension system. The required control force is computed by applying a high‐level controller, which is designed using a linear parameter varying (LPV) method. For the control design the model is augmented with weighting functions specified by the performance demands and the uncertainty assumptions. The actuator generating the necessary control force is modelled as a nonlinear system for which a low‐level force‐tracking controller is designed. To obtain the low‐level controller a backstepping method is proposed. As an alternative solution a feedback linearization method is also presented. The operation of the controller is illustrated through simulation examples. Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society     

Single amino acid substitutions can further increase the stability of a thermophilic L-lactate dehydrogenase

Lactate dehydrogenases are of considerable interest as stereospecificcatalysts in the chemical preparation of enantiomerically pure-hydroxyacid synthons. For such applications in synthetic organicchemistry it would be desirable to have enzymes which tolerateelevated temperatures for prolonged reaction times, to increaseproductivity and to extend then applicability to poor substrates.Here, two examples are reported of significant thermostabilizations,induced by sitedirected mutagenesis, of an already thermostableprotein, the L-lactate dehydrogenase (EC 1.1.1.27 [EC] , 35 kDa permonomer subunit) from Bacillus stearothermophilus. Thermal inactivationof this enzyme is accompanied by irreversible unfolding of thenative protein structure. The replacement of Argl71 by Tyr stabilizesthe enzyme against thermal inactivation and unfolding. Thisstabilizing effect appears to be based on improved interactionsbetween the subunits in the core of the active dimeric or tetramericforms of the enzyme. The thermal stability of L-lactate dehydrogenasevariants with an active site Arg residue, either in the 171(wild-type) or in the 102 position, is further increased bysulfate ions. The two stabilizing effects are additive, as foundfor the Argl71Tyr/ Gln1O2Arg double mutant, for which the stabilityof the protein in 100 mM sulfate solution reaches that of L-lactatedehydrogenases from extreme thermophiles. All mutant proteinsretain significant catalytic activity, both in the presenceand absence of stnhilfoing salts, and are viable catalysts inpreparative scale reactions.     

带式输送机永磁驱动系统自抗扰同步控制策略

针对带式输送机永磁驱动系统采用PID控制器进行控制时电机的控制性能差和采用多电机驱动时电机间转速不同步、稳定性差等问题,提出了带式输送机多永磁电机驱动系统自抗扰同步控制策略。基于自抗扰控制(ADRC)技术设计了2种调速控制策略,并搭建仿真模型进行了对比试验;随后结合模糊PID控制技术对传统偏差耦合控制进行结构改进,并以矿用带式输送机多永磁电机驱动系统为控制对象,开展基于主从、传统偏差耦合和改进型偏差耦合同步控制结构的仿真。结果表明,基于二阶ADRC和改进型偏差耦合控制结构的带式输送机多永磁电机驱动系统同步控制策略具有更好的抗干扰能力、控制精度和同步性,有利于带式输送机平稳高效的安全运行。     

Human DDX3X Unwinds Japanese Encephalitis and Zika Viral 5′ Terminal Regions

Flavivirus genus includes many deadly viruses such as the Japanese encephalitis virus (JEV) and Zika virus (ZIKV). The 5′ terminal regions (TR) of flaviviruses interact with human proteins and such interactions are critical for viral replication. One of the human proteins identified to interact with the 5′ TR of JEV is the DEAD-box helicase, DDX3X. In this study, we in vitro transcribed the 5′ TR of JEV and demonstrated its direct interaction with recombinant DDX3X (K_d of 1.66 ± 0.21 µM) using microscale thermophoresis (MST). Due to the proposed structural similarities of 5′ and 3′ TRs of flaviviruses, we investigated if the ZIKV 5′ TR could also interact with human DDX3X. Our MST studies suggested that DDX3X recognizes ZIKV 5′ TR with a K_d of 7.05 ± 0.75 µM. Next, we performed helicase assays that suggested that the binding of DDX3X leads to the unwinding of JEV and ZIKV 5′ TRs. Overall, our data indicate, for the first time, that DDX3X can directly bind and unwind in vitro transcribed flaviviral TRs. In summary, our work indicates that DDX3X could be further explored as a therapeutic target to inhibit Flaviviral replication     

绳牵引刚柔式波浪补偿并联机构的设计与建模

为了减少海上集装箱货物运输中风浪造成的损坏,提出刚柔混合驱动主动式波浪补偿并联机构. 基于刚柔混合并联机构的动定平台的矩阵旋转原理和几何封闭法建立位置逆解数学模型;利用空间几何原理构建机构位置正解数学模型;利用求导法则对位置逆解进行求导,建立速度雅可比矩阵与加速度的二阶影响矩阵;基于绳子是柔性变形体推导出系统刚度矩阵,探究影响系统刚度的因素和增加系统刚度的原则. 利用数值模拟仿真对运动学和系统刚度进行验证,结果表明位置正逆解的输入输出误差不超过实际误差的2.25%;发现理论仿真曲线和样机仿真曲线较吻合,误差不超过7.4%,验证了运动学模型的正确性;根据刚度矩阵发现刚度影响因素对系统刚度的影响规律. 通过对绳驱动刚柔混合驱动波浪补偿并联机构的实验验证,发现该机构的补偿效果均高于90%. 证明研究结果为刚柔混合主动式波浪补偿并联机构的运动和机构设计提供了理论支持.     

块对角子空间聚类中成对约束的主动式学习

针对块对角表示(block diagonal representation, BDR)子空间聚类算法在对子空间重叠的高维数据聚类时效果较差的问题,提出成对约束的块对角子空间聚类(constrained subspace clustering with block diagonal representation, CBDR)算法,设计主动式学习策略,获取用户提供的少量数据点成对信息,以改进BDR算法的性能,给出CBDR算法的目标函数和求解过程。在测试集上的试验结果表明,CBDR算法的聚类错误率和归一化互信息指标比BDR和SBDR(structured block diagonal representation)算法好,而且主动式选取点对方法优于随机选取点对方法,使用少于5‰的约束信息可降低BDR的聚类错误率达到5%以上。     

Multifunctional heteroatom zeolites: construction and applications

Multifunctional heteroatom zeolites have drawn broad attentions due to the possible synergistic effects in the catalytic reactions. Remarkable achievements have been made on the synthesis, characterization and catalytic applications of multifunctional heteroatom zeolite, while a review on this important topic is still missing. Herein, current research status of multifunctional heteroatom zeolites is briefly summarized, aiming to boost further researches. First, the synthesis strategies toward heteroatom zeolites are introduced, including the direct synthesis and postsynthesis routes; then, the spectroscopic techniques to identify the existing states of heteroatom sites and the corresponding physiochemical properties are shown and compared; finally, the catalytic applications of multifunctional heteroatom zeolites in various chemical reactions, especially in one-step tandem reactions, are discussed.